Set designers don't create cards specifically with Pauper in mind, but due to the dominance of Cranial Plating in that format, it was pretty much a known factor how problematic Cranial Ram would be if it were allowed to run free
Many cards contain text that requires you to flip a coin to determine whether it's successful to give a sense of randomness and balance to specific moves, but almost every player uses a die instead of a coin
Key chase cards include Mew ex #205, Mew ex #208, Mew ex #195, Charizard ex #201, Blastoise ex #202, enusaur ex #200
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Looking for a graded copy
For example, with Breath of Fury on the board along with Najeela and Jegantha, you can take your first combat, tapping Jegantha to activate Najeela